Tau Mutations in Neurodegenerative Diseases
نویسندگان
چکیده
منابع مشابه
Tau mutations in neurodegenerative diseases.
Tau deposition is found in a variety of neurodegenerative brain diseases. The identification of tau mutations that cause familial dementia demonstrated that aberrant Tau alone could cause neurodegenerative disease and suggested that Tau likely plays a role in other cases in which Tau deposits are found, most notably Alzheimer disease. The mechanisms by which tau mutations cause neurodegeneratio...
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1. Inserm, U837, place de Verdun, 59045 Lille, France. 2. Université de Lille 2, Faculté de Médecine, Institut de Médecine prédictive et de Recherche thérapeutique, Centre de Recherches Jean-Pierre Aubert, place de Verdun, 59045 Lille, France. 3. Institut de Biochimie, Centre hospitalier universitaire, UF de Neurobiologie, Lille, France. 4. Innogenetics NV, Industriepark Zwijnaarde 7, 9052 Gent...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.r800013200